TXLNA and STX1B

Data Source:
BioGRID (two hybrid)

		TXLNA	STX1B
Description		taxilin alpha	syntaxin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Membrane	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding Syntaxin Binding	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Exocytosis Cytokine-mediated Signaling Pathway B Cell Activation	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Regulation Of Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Other interleukin signaling	Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		95 interacting genes: AXIN2 AZI2 BIN3 BRCA1 BRMS1L BTF3 BTF3L4 CBY2 CCDC112 CCDC136 CCDC146 CCDC196 CCDC33 CCDC57 CCHCR1 CDC5L CDR2 CEP44 CEP57 CEP57L1 CEP63 CFAP53 DEUP1 DMAP1 DTNB EIF4ENIF1 EPN2 FAM81A FAM9A GAS8 GOLGA2 GOLGA6A GORASP2 HAUS3 HYPK IKBKG KANK2 KIAA1328 KRT13 KRT15 KRT20 KRT24 KRT27 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRT75 LCA5 LZTS1 MBIP MCC MED4 MEOX1 MEOX2 MIS18A NACA NDC80 NKAPD1 NMI NSMCE2 NUP62 OLIG2 PIAS2 PPFIA1 PPP1R13B PRDM16 PRPF3 RASSF8 RCOR3 RINT1 SIKE1 SMARCE1 SNF8 SORBS3 SREK1 STMN2 STX1A STX1B STX3 STX4 TBC1D1 TCL1A TFIP11 TNIP1 TP53BP2 TTC33 TXLNB USHBP1 UTP14C VPS52 WASHC1 WASHC3	29 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB SNAP23 SNAP29 SNAP47 STX2 STX4 STXBP1 TMEM167B TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5
Entrez ID		200081	112755
HPRD ID		09408	18126
Ensembl ID		ENSG00000084652	ENSG00000099365
Uniprot IDs		P40222	P61266
PDB IDs
Enriched GO Terms of Interacting Partners?
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