ELF1 and CD27

Data Source:
HPRD (in vivo)

		ELF1	CD27
Description		E74 like ETS transcription factor 1	CD27 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of B Cell Receptor Signaling Pathway	Cell Surface Receptor Signaling Pathway Immunoglobulin Mediated Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		RUNX1 regulates transcription of genes involved in BCR signaling RUNX1 regulates transcription of genes involved in interleukin signaling	TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Cervical cancer ( 28806749) Crohn's disease ( 23266558) Eosinophil percentage of white cells ( 32888494) Height ( 31562340) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Systemic lupus erythematosus ( 27399966 23273568 21044949) Total cholesterol levels ( 30275531)	Crohn's disease ( 26192919)
Interacting Genes		10 interacting genes: HMGA1 HOXC13 NFKB1 NFYA NFYB NFYC RB1 REL RUNX1 SP1	8 interacting genes: ACTN2 CD70 CIB1 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2
Entrez ID		1997	939
HPRD ID		01808	01723
Ensembl ID		ENSG00000120690	ENSG00000139193
Uniprot IDs		A0A024RDU6 P32519 Q6MZZ4	P26842
PDB IDs			5TL5 5TLJ 5TLK
Enriched GO Terms of Interacting Partners?
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