FCSK and DYNC1LI2

Data Source:
BioGRID (two hybrid)

		FCSK	DYNC1LI2
Description		fucose kinase	dynein cytoplasmic 1 light intermediate chain 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Kinetochore Lysosome Late Endosome Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Membrane
	Molecular Function	Protein Binding ATP Binding Fucokinase Activity	Motor Activity ATP Binding Identical Protein Binding Dynein Heavy Chain Binding
	Biological Process	GDP-L-fucose Salvage Carbohydrate Phosphorylation Response To Dopamine	Microtubule Cytoskeleton Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Centrosome Localization Cellular Response To Nerve Growth Factor Stimulus
Pathways		GDP-fucose biosynthesis	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Lipid traits ( 30576415)
Interacting Genes		2 interacting genes: POGZ TLX3	4 interacting genes: APP BRCA2 DMTN GAA
Entrez ID		197258	1783
HPRD ID		16365	09923
Ensembl ID		ENSG00000157353	ENSG00000135720
Uniprot IDs		Q8N0W3	A0A024R6Z0 O43237 Q63HJ8
PDB IDs			6F1T 6F1Y 6F38 6F3A
Enriched GO Terms of Interacting Partners?
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