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DYNC1LI2 and GAA
Data Source:
BioGRID
(two hybrid)
DYNC1LI2
GAA
Description
dynein cytoplasmic 1 light intermediate chain 2
alpha glucosidase
Image
GO Annotations
Cellular Component
Kinetochore
Lysosome
Late Endosome
Centrosome
Cytosol
Cytoplasmic Dynein Complex
Microtubule
Membrane
Lysosome
Lysosomal Membrane
Plasma Membrane
Membrane
Azurophil Granule Membrane
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Molecular Function
Motor Activity
ATP Binding
Identical Protein Binding
Dynein Heavy Chain Binding
Hydrolase Activity, Hydrolyzing O-glycosyl Compounds
Alpha-1,4-glucosidase Activity
Carbohydrate Binding
Maltose Alpha-glucosidase Activity
Biological Process
Microtubule Cytoskeleton Organization
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule-based Movement
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Centrosome Localization
Cellular Response To Nerve Growth Factor Stimulus
Maltose Metabolic Process
Regulation Of The Force Of Heart Contraction
Diaphragm Contraction
Heart Morphogenesis
Glycogen Catabolic Process
Sucrose Metabolic Process
Glucose Metabolic Process
Lysosome Organization
Locomotory Behavior
Tissue Development
Vacuolar Sequestering
Neutrophil Degranulation
Muscle Cell Cellular Homeostasis
Neuromuscular Process Controlling Posture
Neuromuscular Process Controlling Balance
Cardiac Muscle Contraction
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Glycogen storage disease type II (GAA)
Neutrophil degranulation
Glycogen breakdown (glycogenolysis)
Drugs
Acarbose
Miglitol
AT2220
Diseases
Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Lipid traits (
30576415
)
Blood protein levels (
30072576
)
Platelet distribution width (
32888494
)
Plateletcrit (
32888494
)
Interacting Genes
4 interacting genes:
APP
BRCA2
DMTN
GAA
9 interacting genes:
CPEB2
DYNC1LI2
EP300
HIVEP1
NCF1
NUMBL
PARD3B
SH3GLB2
STAT2
Entrez ID
1783
2548
HPRD ID
09923
06006
Ensembl ID
ENSG00000135720
ENSG00000171298
Uniprot IDs
A0A024R6Z0
O43237
Q63HJ8
P10253
PDB IDs
6F1T
6F1Y
6F38
6F3A
5KZW
5KZX
5NN3
5NN4
5NN5
5NN6
5NN8
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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