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DYNC1LI2

Description dynein cytoplasmic 1 light intermediate chain 2
Image
GO Annotations Cellular Component
  • Kinetochore
  • Lysosome
  • Late Endosome
  • Centrosome
  • Cytosol
  • Cytoplasmic Dynein Complex
  • Microtubule
  • Membrane
Molecular Function
  • Motor Activity
  • ATP Binding
  • Identical Protein Binding
  • Dynein Heavy Chain Binding
Biological Process
  • Microtubule Cytoskeleton Organization
  • Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
  • Microtubule-based Movement
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • Centrosome Localization
  • Cellular Response To Nerve Growth Factor Stimulus
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • MHC class II antigen presentation
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • RHO GTPases Activate Formins
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • Mitotic Prometaphase
  • HCMV Early Events
  • Aggrephagy
  • Aggrephagy
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Lipid traits ( 30576415)
Novel Interacting Genes 4 novel interacting genes: CTRL FCSK HPR ZFHX3
Interacting Genes 4 interacting genes: APP BRCA2 DMTN GAA
Entrez ID 1783
HPRD ID 09923
Ensembl ID ENSG00000135720
Uniprot IDs A0A024R6Z0 O43237 Q63HJ8
PDB IDs 6F1T 6F1Y 6F38 6F3A
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025