DCP1B and NSMAF

Data Source:
BioGRID (two hybrid, pull down)

		DCP1B	NSMAF
Description		decapping mRNA 1B	neutral sphingomyelinase activation associated factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytosol Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol
	Molecular Function	MRNA Binding Protein Binding Enzyme Activator Activity Hydrolase Activity Enzyme Regulator Activity	Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Catalytic Activity Exonucleolytic Catabolism Of Deadenylated MRNA	Ceramide Metabolic Process Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Positive Regulation Of Ceramide Biosynthetic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease	TNFR1-mediated ceramide production
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Grapefruit juice consumption ( 31046077) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Response to gemcitabine in pancreatic cancer ( 22142827) Survival in pancreatic cancer ( 28470677)	Basophil count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		10 interacting genes: DCP2 EDC3 EXOSC6 LSM8 MIR15B NSMAF SMAD4 UPF2 XRN1 ZFP36	6 interacting genes: ACTB CD40 DCP1A DCP1B RACK1 TNFRSF1A
Entrez ID		196513	8439
HPRD ID		13124	09117
Ensembl ID		ENSG00000151065	ENSG00000035681
Uniprot IDs		B4DVJ6 Q8IZD4	Q92636
PDB IDs
Enriched GO Terms of Interacting Partners?
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