SDR16C5 and SNX1

Data Source:
BioGRID (two hybrid)

		SDR16C5	SNX1
Description		short chain dehydrogenase/reductase family 16C member 5	sorting nexin 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Integral Component Of Membrane Transcription Repressor Complex	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Retinol Dehydrogenase Activity Protein Binding Transcription Factor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Activating Transcription Factor Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways		RA biosynthesis pathway
Drugs
Diseases
GWAS		Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Height ( 28552196 20881960 31562340) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: EHHADH EXTL1 FUNDC2 GAD2 HSFX1 HSFX2 NDRG4 NLK SENP2 SNX1 SYT16 TTPA	48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35
Entrez ID		195814	6642
HPRD ID		12351	03171
Ensembl ID		ENSG00000170786	ENSG00000028528
Uniprot IDs		B3KT84 G3V145 Q8N3Y7	Q13596
PDB IDs			2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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