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SNX1 and VPS35
Data Source:
HPRD
(in vivo)
SNX1
VPS35
Description
sorting nexin 1
VPS35 retromer complex component
Image
GO Annotations
Cellular Component
Cytoplasm
Lysosome
Endosome
Golgi Apparatus
Cytosol
Endosome Membrane
Membrane
Lamellipodium
Retromer Complex
Retromer, Tubulation Complex
Early Endosome Membrane
Vesicle
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Mitochondrion
Lysosome
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Cytosol
Endosome Membrane
Retromer Complex
Retromer, Cargo-selective Complex
Extracellular Exosome
Tubular Endosome
Mitochondrion-derived Vesicle
Molecular Function
Epidermal Growth Factor Receptor Binding
Insulin Receptor Binding
Protein Binding
Phosphatidylinositol Binding
Identical Protein Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Heterodimerization Activity
Transferrin Receptor Binding
Leptin Receptor Binding
Protein Binding
D1 Dopamine Receptor Binding
Biological Process
Intracellular Protein Transport
Receptor Internalization
Early Endosome To Golgi Transport
Retrograde Transport, Endosome To Golgi
Positive Regulation Of Protein Catabolic Process
Lamellipodium Morphogenesis
Intracellular Protein Transport
Positive Regulation Of Gene Expression
Regulation Of Mitochondrion Organization
Viral Process
Wnt Signaling Pathway
Regulation Of Macroautophagy
Regulation Of Protein Stability
Regulation Of Cellular Protein Metabolic Process
Protein Localization To Endosome
Retrograde Transport, Endosome To Golgi
Mitochondrial Fragmentation Involved In Apoptotic Process
Transcytosis
Negative Regulation Of Inflammatory Response
Positive Regulation Of Dopamine Receptor Signaling Pathway
Negative Regulation Of Cell Death
Positive Regulation Of Mitochondrial Fission
Mitochondrion To Lysosome Transport
Neurotransmitter Receptor Transport, Endosome To Plasma Membrane
Negative Regulation Of Neuron Death
Negative Regulation Of Late Endosome To Lysosome Transport
Regulation Of Dendritic Spine Maintenance
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Presynapse Assembly
Retrograde Transport, Endosome To Plasma Membrane
Regulation Of Terminal Button Organization
Pathways
WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS
Interacting Genes
48 interacting genes:
ACVR1B
ACVR2B
AGTRAP
APP
ARFIP2
ARL6IP1
ARMC12
ATXN7
CCDC148
CHRNG
CMTM4
CMTM5
COQ3
EGFR
F2R
FAM25A
FAM25C
FAM25G
FKBP7
FUNDC1
HCCS
HGS
INSR
LEPR
LIME1
MPC2
PDGFRB
PLIN3
RABAC1
REEP5
REEP6
RHEX
RTN3
RTN4
SASH1
SDCBP
SDR16C5
SFT2D1
SH3GLB1
SNX2
SNX32
SNX6
SYNGR1
SYP
TK1
TMEM239
UFD1
VPS35
12 interacting genes:
APP
DRD1
LINC01554
MTNR1B
SLC11A2
SNX1
SNX3
VEGFA
VPS26A
VPS26B
VPS29
ZNF512B
Entrez ID
6642
55737
HPRD ID
03171
06085
Ensembl ID
ENSG00000028528
ENSG00000069329
Uniprot IDs
Q13596
Q96QK1
PDB IDs
2I4K
4FZS
2R17
5F0J
5F0K
5F0L
5F0M
5F0P
5OSH
5OSI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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