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PHC2 and TRIM41
Data Source:
BioGRID
(two hybrid)
PHC2
TRIM41
Description
polyhomeotic homolog 2
tripartite motif containing 41
Image
No pdb structure
GO Annotations
Cellular Component
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Nucleolus
Cytoplasm
Nuclear Body
Molecular Function
DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
Histone Binding
Identical Protein Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Biological Process
Multicellular Organism Development
Spermatogenesis
Negative Regulation Of Transcription, DNA-templated
Protein Ubiquitination
Positive Regulation Of DNA-binding Transcription Factor Activity
Cellular Response To Lipopolysaccharide
Cellular Response To Muramyl Dipeptide
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Adventurousness (
30643258
)
Blood urea nitrogen levels (
31152163
29403010
)
General risk tolerance (MTAG) (
30643258
)
Pulse pressure (
30224653
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking status (ever vs never smokers) (
30643258
)
Urinary albumin excretion (
30220432
)
Urinary albumin-to-creatinine ratio (
31630189
)
Interacting Genes
79 interacting genes:
AEN
AFG3L2
AP1M1
BMI1
BSDC1
BYSL
C1orf109
CARD9
CBX2
CRK
CRKL
CSNK2B
DRG1
ENKD1
FAM124A
FAM13C
FAM161A
FAM74A1
FAM74A4
FHL3
FOSB
GFI1B
GRB2
H3-4
HDAC7
KAT5
KBTBD7
KDM1A
KIFC3
KLHDC7B
KRT31
L3MBTL3
LMO1
LMO2
LMO3
MAB21L3
MAGEB6
MAPK14
MAPK6
MAPKAPK2
MCM2
MCRS1
MFAP1
MLLT6
MORF4L2
NCK1
PCGF2
PCGF3
PCGF5
PHC1
PLAGL2
PLK1
POLR2L
PPP1R16B
PRKAA1
PRPF3
PRPF31
RBM39
RNF2
RPL7
RWDD2B
SCMH1
SDCBP
SFMBT1
SIAH1
SMAD3
SPATC1L
SSX2IP
SYT16
TAB1
THAP7
TMEM70
TRIM41
TRIM55
TRIM63
ZBTB24
ZGPAT
ZMAT2
ZNF417
140 interacting genes:
AEN
AKTIP
ANKRD23
AP1M1
APP
AQP1
BIVM
BRAP
BYSL
C8orf33
CARD10
CCNL2
CEP44
CHD2
CSNK2A1
CSNK2A2
DEPTOR
DVL3
EHHADH
EZHIP
FAM124A
FAM161A
FAM9A
FLACC1
FRA10AC1
GAS8
GPATCH2L
IKBKG
JRK
KATNBL1
KIFC3
KRTAP10-8
KRTAP10-9
MAGEH1
MCRS1
MEOX1
MEOX2
MFAP1
MID2
MOBP
MORF4L1
MORF4L2
MPP3
NCK2
NEDD4L
NOD2
PBX4
PHC2
PHF11
PHF7
PLAGL2
PRDM14
PRKCA
PRKCB
PRPF31
PTPN3
PUS7L
RBAK
RNPS1
SORBS3
SRPK2
STX11
SUV39H1
SYCE1
SYTL4
TBC1D26
TCEA2
TCEANC
TLE5
TNNI1
TOP3B
TRAIP
TRIM17
TRIM26
TRIM4
TRIM52
TRIM55
TRIM63
UBE2D2
UBE2I
ZBTB24
ZBTB26
ZBTB38
ZBTB39
ZBTB48
ZBTB8A
ZCCHC7
ZFP1
ZFP2
ZFP64
ZMAT5
ZNF121
ZNF134
ZNF138
ZNF165
ZNF2
ZNF219
ZNF24
ZNF250
ZNF251
ZNF26
ZNF263
ZNF264
ZNF266
ZNF275
ZNF286A
ZNF319
ZNF329
ZNF343
ZNF398
ZNF408
ZNF417
ZNF439
ZNF460
ZNF473
ZNF48
ZNF490
ZNF497
ZNF526
ZNF552
ZNF564
ZNF575
ZNF587
ZNF629
ZNF648
ZNF653
ZNF655
ZNF670
ZNF691
ZNF696
ZNF71
ZNF773
ZNF780A
ZNF784
ZNF792
ZNF835
ZNF837
ZSCAN16
ZSCAN21
ZSCAN26
Entrez ID
1912
90933
HPRD ID
10340
15558
Ensembl ID
ENSG00000134686
ENSG00000146063
Uniprot IDs
A0A0A0MSI2
Q8IXK0
Q8WV44
PDB IDs
2EGM
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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