E2F6 and ZMYND11

Data Source:
HPRD (in vitro, in vivo)

		E2F6	ZMYND11
Description		E2F transcription factor 6	zinc finger MYND-type containing 11
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm MLL1 Complex RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition	Chromatin Organization Cell Cycle Viral Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Sudden cardiac arrest ( 21658281)	Malaria ( 31844061)
Interacting Genes		27 interacting genes: APP ARAF BMI1 BRDT CENPU DNMT1 DNMT3L DNTTIP1 E2F1 EPC1 EZH1 EZH2 HMG20B INO80B KRTAP10-7 NFYA PCGF6 PIK3R3 RING1 RYBP SMARCA4 TFDP1 TFDP2 ZBTB17 ZBTB32 ZFPM2 ZMYND11	24 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1
Entrez ID		1876	10771
HPRD ID		04251	09830
Ensembl ID		ENSG00000169016	ENSG00000015171
Uniprot IDs		A0A0S2Z3K8 O75461 Q53YM3 Q6Q9Z5	B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2
PDB IDs			4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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