DMBT1 and PRSS2

Data Source:
BioGRID (affinity chromatography technology)

		DMBT1	PRSS2
Description		deleted in malignant brain tumors 1	serine protease 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome	Extracellular Region Extracellular Space Extracellular Matrix Azurophil Granule Lumen
	Molecular Function	Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding Extracellular Matrix Binding	Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Endocytosis Defense Response Multicellular Organism Development Protein Transport Viral Process Epithelial Cell Differentiation Detection Of Bacterial Lipoprotein Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus	Proteolysis Digestion Antimicrobial Humoral Response Extracellular Matrix Disassembly Positive Regulation Of Cell Growth Collagen Catabolic Process Neutrophil Degranulation Positive Regulation Of Cell Adhesion
Pathways		Surfactant metabolism	Collagen degradation Alpha-defensins Activation of Matrix Metalloproteinases Neutrophil degranulation Antimicrobial peptides
Drugs			Monoisopropylphosphorylserine O-Benzylsulfonyl-Serine Benzylamine Benzamidine Phosphorylisopropane Phenethylamine 3-Phenylpropylamine
Diseases			Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Iris heterochromicity ( 30895295)	Blood protein levels ( 29875488) Pancreatitis ( 23143602)
Interacting Genes		2 interacting genes: SFTPA1 SFTPD	7 interacting genes: APP BPI CSN1S1 GLP1R MMP9 SERPINA1 SLPI
Entrez ID		1755	5645
HPRD ID		03575	03335
Ensembl ID		ENSG00000187908	ENSG00000275896
Uniprot IDs		A0A590UJ76 Q9UGM3	A6XMV9 P07478 Q5NV56 Q6PK75
PDB IDs		6SA4 6SA5 6SAN
Enriched GO Terms of Interacting Partners?
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