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PRSS2

Description serine protease 2
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Extracellular Matrix
  • Azurophil Granule Lumen
Molecular Function
  • Serine-type Endopeptidase Activity
  • Calcium Ion Binding
  • Protein Binding
Biological Process
  • Proteolysis
  • Digestion
  • Antimicrobial Humoral Response
  • Extracellular Matrix Disassembly
  • Positive Regulation Of Cell Growth
  • Collagen Catabolic Process
  • Neutrophil Degranulation
  • Positive Regulation Of Cell Adhesion
Pathways
  • Collagen degradation
  • Alpha-defensins
  • Activation of Matrix Metalloproteinases
  • Neutrophil degranulation
  • Antimicrobial peptides
Drugs
  • Monoisopropylphosphorylserine
  • O-Benzylsulfonyl-Serine
  • Benzylamine
  • Benzamidine
  • Phosphorylisopropane
  • Phenethylamine
  • 3-Phenylpropylamine
Diseases
  • Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS
  • Blood protein levels ( 29875488)
  • Pancreatitis ( 23143602)
Novel Interacting Genes 2 novel interacting genes: DMBT1 MKKS
Interacting Genes 7 interacting genes: APP BPI CSN1S1 GLP1R MMP9 SERPINA1 SLPI
Entrez ID 5645
HPRD ID 03335
Ensembl ID ENSG00000275896
Uniprot IDs A6XMV9 P07478 Q5NV56 Q6PK75
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025