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DLG3 and DLGAP4
Data Source:
HPRD
(two hybrid)
DLG3
DLGAP4
Description
discs large MAGUK scaffold protein 3
DLG associated protein 4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytosol
Plasma Membrane
Ionotropic Glutamate Receptor Complex
Basolateral Plasma Membrane
Cell Junction
Plasma Membrane
Neuromuscular Junction
Glutamatergic Synapse
Cholinergic Synapse
Postsynaptic Specialization
Molecular Function
Protein Binding
Kinase Binding
Phosphatase Binding
Protein Binding
Molecular Adaptor Activity
Biological Process
MAPK Cascade
Negative Regulation Of Cell Population Proliferation
Embryo Development
Negative Regulation Of Phosphatase Activity
Receptor Clustering
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Protein Tyrosine Kinase Activity
Receptor Localization To Synapse
Cell-cell Adhesion
Regulation Of NMDA Receptor Activity
Signaling
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways
Unblocking of NMDA receptors, glutamate binding and activation
Unblocking of NMDA receptors, glutamate binding and activation
Ras activation upon Ca2+ influx through NMDA receptor
NrCAM interactions
Activation of Ca-permeable Kainate Receptor
RAF/MAP kinase cascade
Neurexins and neuroligins
Neurexins and neuroligins
Synaptic adhesion-like molecules
Assembly and cell surface presentation of NMDA receptors
Negative regulation of NMDA receptor-mediated neuronal transmission
Long-term potentiation
Neurexins and neuroligins
Neurexins and neuroligins
Drugs
Diseases
Non-syndromic X-linked mental retardation
GWAS
Mean platelet volume (
32888494
)
Low density lipoprotein cholesterol levels (
32154731
)
Neuroblastoma or malignant cutaneous melanoma (
31605138
)
Interacting Genes
48 interacting genes:
ABCA1
ADGRL1
APC
ATP2B4
CACNG2
CALM1
CNKSR2
CRIPT
DHRS11
DLG1
DLG4
DLGAP1
DLGAP2
DLGAP3
DLGAP4
EIF4H
ERBB4
EXOC4
EXOC7
GDA
GLS2
GRIK2
GRIN1
GRIN2A
GRIN2B
GRIN2C
GUCY1A2
KCNA4
KCNJ12
KCNJ2
KDELR1
KHDRBS1
KIF1B
LIN7A
LRP2
MAPK12
NLGN1
NLGN2
NLGN3
OSBP2
PLEKHA2
PTK2B
RPS8
SCN4A
SCN5A
SEMA4C
SYNGAP1
VTN
32 interacting genes:
ABI2
ALDH16A1
ATPAF2
BIN1
DLG1
DLG3
DLG4
EXOC4
FHL3
FHL5
FKBP6
FYN
GRIN1
GRIN2D
MAGEA6
MPP7
MTUS2
NCK1
NCK2
PALS1
PLP2
PPP1R1B
SH3GL2
SH3RF1
SHANK2
SHANK3
SLC9A3R1
SLC9A3R2
SORBS2
SYNGAP1
UBASH3A
UBC
Entrez ID
1741
22839
HPRD ID
02177
16826
Ensembl ID
ENSG00000082458
ENSG00000080845
Uniprot IDs
Q59FY1
Q92796
A0A0B4J2C2
Q9Y2H0
PDB IDs
1UM7
2FE5
2I1N
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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