DHPS and NUDT18

		DHPS	NUDT18
Description		deoxyhypusine synthase	nudix hydrolase 18
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytosol
	Molecular Function	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Platelet distribution width ( 32888494)
Interacting Genes		16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138	34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1
Entrez ID		1725	79873
HPRD ID		02969	07992
Ensembl ID		ENSG00000095059	ENSG00000275074
Uniprot IDs		A0A024R7D0 A0A024R7E9 P49366	Q6ZVK8
PDB IDs		1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM	3GG6 4HVY
Enriched GO Terms of Interacting Partners?
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