DHPS and EIF5A2

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		DHPS	EIF5A2
Description		deoxyhypusine synthase	eukaryotic translation initiation factor 5A2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nuclear Pore Endoplasmic Reticulum Membrane Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding	Translation Elongation Factor Activity Protein Binding Ribosome Binding
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine	Translational Elongation Spermatogenesis Positive Regulation Of Cell Population Proliferation Polyamine Homeostasis Protein Transport Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination MRNA Transport
Pathways		Hypusine synthesis from eIF5A-lysine	Hypusine synthesis from eIF5A-lysine
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Platelet distribution width ( 32888494)	C-reactive protein levels ( 30388399) Urate levels ( 31578528)
Interacting Genes		16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138	8 interacting genes: CDC23 DHPS HIF1A NIF3L1 PTBP2 RAB30 REL SDCBP
Entrez ID		1725	56648
HPRD ID		02969	10426
Ensembl ID		ENSG00000095059	ENSG00000163577
Uniprot IDs		A0A024R7D0 A0A024R7E9 P49366	Q9GZV4
PDB IDs		1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM
Enriched GO Terms of Interacting Partners?
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