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DHPS and VASH1
Data Source:
BioGRID
(two hybrid)
DHPS
VASH1
Description
deoxyhypusine synthase
vasohibin 1
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Extracellular Space
Cytoplasm
Endoplasmic Reticulum
Apical Part Of Cell
Molecular Function
Protein Binding
Deoxyhypusine Synthase Activity
Identical Protein Binding
Actin Binding
Metallocarboxypeptidase Activity
Protein Binding
Biological Process
Translation
Spermidine Metabolic Process
Positive Regulation Of Cell Population Proliferation
Peptidyl-lysine Modification To Peptidyl-hypusine
Angiogenesis
Negative Regulation Of Endothelial Cell Proliferation
Proteolysis
Cell Cycle Arrest
Response To Wounding
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Angiogenesis
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Angiogenesis
Labyrinthine Layer Blood Vessel Development
Negative Regulation Of Lymphangiogenesis
Regulation Of Cellular Senescence
Pathways
Hypusine synthesis from eIF5A-lysine
Carboxyterminal post-translational modifications of tubulin
Drugs
1-Guanidinium-7-Aminoheptane
Diseases
GWAS
Platelet distribution width (
32888494
)
Interacting Genes
16 interacting genes:
BRCA1
EIF5A
EIF5A2
LNX1
MEOX2
NIF3L1
NTAQ1
NUDT18
PAX6
PTPRH
RAB27B
RBP1
REL
RPL9
VASH1
ZNF138
1 interacting genes:
DHPS
Entrez ID
1725
22846
HPRD ID
02969
12353
Ensembl ID
ENSG00000095059
ENSG00000071246
Uniprot IDs
A0A024R7D0
A0A024R7E9
P49366
Q7L8A9
PDB IDs
1DHS
1RLZ
1ROZ
1RQD
6P4V
6PGR
6WKZ
6WL6
6XXH
6XXI
6XXJ
6XXK
6XXL
6XXM
6J4U
6J7B
6J8F
6J8N
6J8O
6J91
6J9H
6K81
6LPG
6NVQ
6OCF
6OCG
6OCH
6WSL
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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