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FAM9B and STK3
Data Source:
BioGRID
(two hybrid)
FAM9B
STK3
Description
family with sequence similarity 9 member B
serine/threonine kinase 3
Image
No pdb structure
GO Annotations
Cellular Component
Synaptonemal Complex
Nucleoplasm
Nucleus
Cytoplasm
Cytosol
Protein-containing Complex
Molecular Function
Protein Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Protein Serine/threonine Kinase Activator Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Spermatid Development
Meiotic Cell Cycle
Neural Tube Formation
Endocardium Development
Protein Phosphorylation
Apoptotic Process
Central Nervous System Development
Negative Regulation Of Cell Population Proliferation
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Protein Binding
Activation Of Protein Kinase Activity
Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of JNK Cascade
Negative Regulation Of Organ Growth
Protein Stabilization
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Protein Kinase B Signaling
Primitive Hemopoiesis
Cell Differentiation Involved In Embryonic Placenta Development
Regulation Of Cell Differentiation Involved In Embryonic Placenta Development
Positive Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Hepatocyte Apoptotic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Signaling by Hippo
Drugs
Fostamatinib
Diseases
GWAS
Age at voice drop (
27182965
)
Androgen levels (
22936694
)
Creatinine levels (
29403010
)
Glomerular filtration rate (
29403010
)
Heel bone mineral density (
30598549
28869591
)
Hematocrit (
29403010
)
Hemoglobin (
29403010
)
Male-pattern baldness (
29146897
27182965
)
Metabolite levels (
23823483
)
Depressive symptom improvement (
30468137
)
Heel bone mineral density (
30598549
)
Rosacea symptom severity (
29771307
)
Suicide behavior (
26079190
)
Interacting Genes
142 interacting genes:
ABT1
ACP6
ANKRD36B
AP1M1
ASB6
ATF7
AURKAIP1
BAG6
BAIAP2L2
BARD1
BCL2A1
BET1
BLOC1S2
BRME1
BYSL
C16orf72
C8orf33
CADPS
CCDC106
CCDC116
CCDC198
CCDC70
CDC23
CDC37
CDC42EP4
CDCA7L
CDSN
CENPL
CEP57L1
CEP95
CHRAC1
CLCN1
CMTM6
COL20A1
CSDE1
CWF19L2
DAPK2
DAXX
DENND2D
DGUOK
DNAJC15
DNAJC4
EBNA1BP2
ECH1
EIF3G
ELOA
FAM161A
FAM9A
FASTKD3
FCHSD2
FERD3L
FNDC11
GFOD1
GOPC
GPX1
GRAMD4
GSTK1
HNRNPLL
IBSP
ISCU
JAZF1
LBX1
LIN7A
LINC02363
LMNA
LNX1
LYRM2
MAB21L3
MFAP1
MOB1A
MORF4L1
MORF4L2
MRPL10
MRPL28
MRPL9
MRRF
MYG1
MYO15B
NDE1
NDUFB10
NEBL
NOL4
NOTO
PAGE1
PAGE3
PHYH
PIN4
POLL
PPARA
PPP1R18
PRPF3
PSMD14
PTRH1
RAB17
RAD51B
RBM17
RBM23
RMND1
RNF8
RPL9
RSL24D1
RUBCN
RUSC1
SDCBP
SDCBP2
SERPINE2
SFN
SLC16A3
SLPI
SMARCB1
SMN1
SMN2
SNAP29
SNAP47
SNX20
SRRM4
STK3
SUCLA2
SURF6
SYT17
TBC1D25
TBRG4
TCEA2
TCEANC
TGFBI
TOM1L2
TRMT61B
TSG101
TUFM
TXN2
UBE2E2
URB1-AS1
WT1
XRCC4
YARS2
ZCCHC10
ZGPAT
ZNF41
ZNF410
ZNF567
ZNF614
ZNF777
40 interacting genes:
AKT1
CASP3
CDK1
CNKSR1
CPNE1
DDAH2
EIF4EBP1
FAM9B
GAD1
GBP2
GMCL1
HSPE1
KEAP1
KHSRP
LATS1
LATS2
LRRK2
MARK2
MBP
MOB1B
MOB3B
MOB4
MPP1
ORM2
PEX19
PHAX
PLK1
QARS1
RAF1
RASSF1
RASSF2
RASSF4
SAV1
SLMAP
SNIP1
STK4
SULT2A1
TFPT
TRAF1
ZC3H7A
Entrez ID
171483
6788
HPRD ID
15955
05433
Ensembl ID
ENSG00000177138
ENSG00000104375
Uniprot IDs
A0A024RBV3
Q8IZU0
A0A087WZ06
A0A384MR07
Q13188
PDB IDs
3WWS
4HKD
4L0N
4LG4
4LGD
4OH9
5BRM
5DH3
6AO5
6AR2
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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