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DDX1 and MIR31
Data Source:
BioGRID
(unspecified method)
DDX1
MIR31
Description
DEAD-box helicase 1
microRNA 31
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoplasmic Stress Granule
Membrane
Cleavage Body
TRNA-splicing Ligase Complex
Ribonucleoprotein Complex
Extracellular Space
RISC Complex
Microvesicle
Molecular Function
DNA Binding
Chromatin Binding
Transcription Coregulator Activity
RNA Binding
RNA Helicase Activity
Helicase Activity
Nuclease Activity
Exonuclease Activity
Protein Binding
ATP Binding
Poly(A) Binding
DNA/RNA Helicase Activity
MRNA 3'-UTR Binding
Protein Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
MRNA CDS Binding
Biological Process
Spliceosomal Complex Assembly
Double-strand Break Repair
Regulation Of Transcription, DNA-templated
TRNA Splicing, Via Endonucleolytic Cleavage And Ligation
Regulation Of Translational Initiation
Multicellular Organism Development
Viral Process
DNA Duplex Unwinding
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Defense Response To Virus
Nucleic Acid Phosphodiester Bond Hydrolysis
Protein Localization To Cytoplasmic Stress Granule
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Interleukin-34 Production
Positive Regulation Of Sprouting Angiogenesis
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Negative Regulation Of Amyloid Fibril Formation
Pathways
tRNA processing in the nucleus
Drugs
Diseases
GWAS
Asthma or chronic obstructive pulmonary disease (
24993907
)
Blood urea nitrogen levels (
31152163
)
Chronic kidney disease (
22479191
)
Chronic obstructive pulmonary disease (
30804561
)
Estimated glomerular filtration rate (
31152163
31015462
31451708
30604766
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Glomerular filtration rate (creatinine) (
28452372
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Metabolite levels (
23823483
)
Pulmonary function (
21946350
)
Pulmonary function (smoking interaction) (
23284291
)
Severe COVID-19 infection with respiratory failure (analysis I) (
32558485
)
Urate levels (
31578528
)
Wilms tumor (
22544364
)
Interacting Genes
83 interacting genes:
APP
ATM
CSTF2
ESR1
HNRNPK
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NDRG1
NME7
PTEN
RELA
SUMO2
YWHAQ
83 interacting genes:
ADARB1
AIMP1
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MYEF2
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PTBP1
PTBP3
PUF60
PURA
PURB
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
STRBP
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
1653
407035
HPRD ID
03158
Ensembl ID
ENSG00000079785
ENSG00000199177
Uniprot IDs
A3RJH1
Q92499
PDB IDs
4XW3
Enriched GO Terms of Interacting Partners
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