DGKQ and NBPF19

Data Source:
BioGRID (two hybrid)

		DGKQ	NBPF19
Description		diacylglycerol kinase theta	NBPF member 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane Vesicle Membrane Nuclear Matrix Nuclear Speck Presynapse Postsynapse Glutamatergic Synapse	Cytoplasm
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Binding Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Activating Transcription Factor Binding Phospholipase Binding Metal Ion Binding
	Biological Process	Regulation Of Gluconeogenesis Regulation Of Transcription By RNA Polymerase II Phosphatidic Acid Biosynthetic Process Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity G Protein-coupled Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Peptidyl-threonine Phosphorylation Peptidyl-serine Phosphorylation CAMP-mediated Signaling Platelet Activation Response To ATP Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Response To CAMP Thrombin-activated Receptor Signaling Pathway Protein Kinase C Signaling Regulation Of Cholesterol Metabolic Process Regulation Of Synaptic Vesicle Endocytosis Regulation Of TORC1 Signaling Regulation Of Cortisol Biosynthetic Process Regulation Of Progesterone Biosynthetic Process
Pathways		Effects of PIP2 hydrolysis
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Idiopathic inflammatory myopathy ( 26362759) Limited cutaneous systemic scleroderma ( 29293537) Parkinson's disease ( 22451204 25064009 28892059 22438815 20070850 32310270) Parkinson's disease (familial) ( 18985386) Primary biliary cholangitis ( 26394269) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 28714469) Systemic sclerosis ( 31672989 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Triglyceride levels ( 32203549) Waist circumference ( 31928498)	Serum uric acid levels ( 30993211)
Interacting Genes		3 interacting genes: NBPF19 NOTCH2NLA RHOA	223 interacting genes: ADAM12 ADAMTSL4 AGXT ALDH16A1 ALPP ANKS1A AQP1 ATG9A ATP5F1D BCAM BMP7 BRME1 CARHSP1 CATSPER1 CCER1 CD164 CELF5 CERK CHCHD3 CHIC2 CHRD CHRNG CNNM3 COL8A1 CREB5 CRH CRY2 CST2 CST9L CTNNBIP1 CTSZ CXCL16 CYHR1 CYP21A2 CYSRT1 DAGLB DALRD3 DBH DGKQ DHRS1 DMRT3 DOCK2 DRD5 EMC7 F10 FADS2 FAM221A FAM71C FAM90A1 FBXW5 FRS3 FTHL17 FZD10 GLP1R GLYAT GNE GSTP1 HAPLN2 HBA1 HBA2 HBZ HCK HHEX HOXA1 HOXB9 HOXC8 HPCAL1 HSPA12B ICAM4 IL10 INO80B INS ITGB2 ITGB4 ITGB5 JOSD1 KCNS2 KCTD15 KLHL38 KLK8 KPRP KRT83 KRTAP10-1 KRTAP10-10 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 LRFN4 LYVE1 MACO1 MAPKBP1 MELTF MFSD13A MOS MRGBP MRPL40 MTA1 MXD3 MXI1 MYO15B MYPOP NECTIN2 NECTIN3 NEDD9 NMU NPDC1 NR1D2 NTM NTN4 OLFM2 OTX1 P2RX4 P2RX7 P2RY6 PCSK5 PGAP6 PHLDA1 PIGS PLEKHN1 PRF1 PRR35 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAB3IL1 RAMP3 RASD1 RECK RNF111 RPS19BP1 RTN4RL1 SCNM1 SEMA3B SEMA4C SHFL SLC22A5 SLC23A1 SLC43A2 SLC5A5 SLC6A20 SMCP SPATA24 SPATA8 SPG7 SPPL2C SPRY1 STAC STK16 TAPBPL TCAF1 THAP7 TLE5 TMEFF2 TMEM150A TMIE TNIP3 TNS2 TRAPPC14 TRIM42 TROAP TSPAN4 TTPA UTP23 UXT VASN WDR25 ZDHHC1 ZNF124 ZNF319 ZNF330 ZNF408 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF580 ZNF581 ZNF587 ZNF648 ZNF672 ZNF786 ZNF837
Entrez ID		1609	101060226
HPRD ID		03127
Ensembl ID		ENSG00000145214	ENSG00000271383
Uniprot IDs		A0A140VKC1 P52824 Q59FF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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