SYT6 and FXR2

Data Source:
BioGRID (two hybrid, two hybrid)

		SYT6	FXR2
Description		synaptotagmin 6	FMR1 autosomal homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Synaptic Vesicle Membrane Exocytic Vesicle Perinuclear Endoplasmic Reticulum Glutamatergic Synapse Integral Component Of Synaptic Membrane	Nucleus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Presynapse Dendritic Filopodium
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Protein Homodimerization Activity	RNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Acrosomal Vesicle Exocytosis Cellular Response To Calcium Ion Presynaptic Dense Core Vesicle Exocytosis	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Response To DNA Damage Stimulus
Pathways
Drugs
Diseases
GWAS		Breast cancer (prognosis) ( 23319801) Obesity-related traits ( 23251661) Refractive error ( 32231278)	Atrial fibrillation ( 30061737) Brain morphology (MOSTest) ( 32665545) IgM levels ( 23118916) Refractive error ( 32231278) Sex hormone-binding globulin levels ( 22675492)
Interacting Genes		30 interacting genes: APP BRCA1 CCDC136 CCDC57 CNTROB DVL3 FXR1 FXR2 GMCL1 GOLGA2 HMBOX1 HOOK2 KANK2 KCTD9 KIF24 KIFC3 KRT40 LMNA LZTS1 MAD1L1 MCC MTUS2 NRXN1 PRKCB TNIP1 TRIM27 TRIM32 TSGA10 ZBTB43 ZBTB8A	107 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BLK BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CBS CCDC33 CCDC85B CCR4 CDKL3 CEP44 CEP55 COIL CWF19L2 CYFIP1 CYFIP2 DDX17 DMRTB1 DPPA2 DYNLT1 EIF4G1 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 GTSE1 HMBOX1 HNRNPC IGFN1 INPP5J KCNRG KCTD4 KIAA1217 KIF1A KIF2A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDEL1 NDN NECAB2 NEXN NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PIM1 POM121 PRAM1 PRC1 PSME3 PTS RABAC1 RALYL RBBP8 RBM14 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF232 ZNF451 ZNRD2 ZSCAN1
Entrez ID		148281	9513
HPRD ID		09654	05629
Ensembl ID		ENSG00000134207	ENSG00000129245
Uniprot IDs		I6L9C3 Q5T7P8	P51116
PDB IDs			3H8Z
Enriched GO Terms of Interacting Partners?
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