SYT6 and ZBTB43

Data Source:
BioGRID (two hybrid)

		SYT6	ZBTB43
Description		synaptotagmin 6	zinc finger and BTB domain containing 43
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Synaptic Vesicle Membrane Exocytic Vesicle Perinuclear Endoplasmic Reticulum Glutamatergic Synapse Integral Component Of Synaptic Membrane	Chromatin Nucleus
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Protein Homodimerization Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Acrosomal Vesicle Exocytosis Cellular Response To Calcium Ion Presynaptic Dense Core Vesicle Exocytosis	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Breast cancer (prognosis) ( 23319801) Obesity-related traits ( 23251661) Refractive error ( 32231278)	BMI (adjusted for smoking behaviour) ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Eyebrow thickness ( 26926045)
Interacting Genes		30 interacting genes: APP BRCA1 CCDC136 CCDC57 CNTROB DVL3 FXR1 FXR2 GMCL1 GOLGA2 HMBOX1 HOOK2 KANK2 KCTD9 KIF24 KIFC3 KRT40 LMNA LZTS1 MAD1L1 MCC MTUS2 NRXN1 PRKCB TNIP1 TRIM27 TRIM32 TSGA10 ZBTB43 ZBTB8A	27 interacting genes: AEN AP1M1 ARR3 ARRB1 BDP1 CCDC13 CDKL3 CIB3 DDX6 DIP2A ELOA2 FAM161A LMO1 LMO3 LMO4 LNX1 MCM10 MORF4L1 MORF4L2 PSMD3 SYT6 TCEA2 TRAF2 ZBTB24 ZNF250 ZNF417 ZNF587
Entrez ID		148281	23099
HPRD ID		09654	08346
Ensembl ID		ENSG00000134207	ENSG00000169155
Uniprot IDs		I6L9C3 Q5T7P8	O43298
PDB IDs			2CSH
Enriched GO Terms of Interacting Partners?
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