C18orf25 and TAX1BP1

Data Source:
BioGRID (two hybrid)

		C18orf25	TAX1BP1
Description		chromosome 18 open reading frame 25	Tax1 binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process
Pathways			Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 29274321) Clinical laboratory measurements ( 27897004) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: DDIT4L JAKMIP1 LRRK2 MCRS1 RNF4 SRPK1 SRPK2 SUMO1 SUMO1P1 SUMO2 TAX1BP1 UBE2I	75 interacting genes: ARHGAP1 AZI2 C18orf25 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN EMILIN1 FAM161A FAM168A FAM189A2 FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LGALS8 LITAF LMO3 LNX1 LRATD2 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RB1CC1 RIPK1 RNF11 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP1 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446
Entrez ID		147339	8887
HPRD ID		12690	05618
Ensembl ID		ENSG00000152242	ENSG00000106052
Uniprot IDs		Q96B23	B4DSG5 Q86VP1
PDB IDs			2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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