KRT25 and KRT6A

Data Source:
BioGRID (two hybrid)

		KRT25	KRT6A
Description		keratin 25	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Molecular_function Structural Molecule Activity Protein Binding Protein Heterodimerization Activity	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Cytoskeleton Organization Aging Hair Follicle Morphogenesis Keratinization Hair Cycle Intermediate Filament Organization Cornification	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Asthma ( 31959851 30929738) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		22 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT83 KRT85 KRT86 MORN4 PPL	38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		147183	3853
HPRD ID		17242	01011
Ensembl ID		ENSG00000204897	ENSG00000205420
Uniprot IDs		Q6ZPD6 Q7Z3Z0	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?
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