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KRT6A and BEX2
Data Source:
BioGRID
(two hybrid)
KRT6A
BEX2
Description
keratin 6A
brain expressed X-linked 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Membrane
Keratin Filament
Extracellular Exosome
Nucleus
Cytoplasm
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Signaling Receptor Binding
Protein Binding
Biological Process
Negative Regulation Of Cytolysis By Symbiont Of Host Cells
Morphogenesis Of An Epithelium
Cytoskeleton Organization
Positive Regulation Of Cell Population Proliferation
Cell Differentiation
Keratinization
Wound Healing
Defense Response To Gram-positive Bacterium
Cytolysis By Host Of Symbiont Cells
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cornification
Negative Regulation Of Entry Of Bacterium Into Host Cell
Apoptotic Process
Cell Cycle
Signal Transduction
Regulation Of Apoptotic Process
Regulation Of Cell Cycle
Pathways
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Zinc acetate
Diseases
Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Cutaneous squamous cell carcinoma (
32041948
)
Interacting Genes
38 interacting genes:
BEX2
CCDC85B
DSP
GEM
GOLGA2
HGS
KDM1A
KIFC3
KRT13
KRT15
KRT16
KRT17
KRT18
KRT19
KRT25
KRT26
KRT27
KRT28
KRT31
KRT34
KRT35
KRT36
KRT38
KRT40
LMNA
MTUS2
NCALD
NUP62
SGTA
SMARCB1
TCHP
TFIP11
TRIM23
TRIM54
TSGA10
TXLNB
UBQLN2
WASHC3
92 interacting genes:
AKAP9
AURKA
BCAR3
BHLHB9
BLZF1
BORCS6
BRMS1
CALCOCO2
CCDC197
CCDC57
CCDC85B
CCDC88B
CDR2
CEP70
COG4
CTAG1A
CTAG1B
CYSRT1
EXOC8
FGFR2
FSD2
FST
HSF2BP
HSPB2
HSPB2-C11orf52
KLHL20
KNSTRN
KRT15
KRT19
KRT27
KRT31
KRT34
KRT38
KRT39
KRT40
KRT6A
KRT75
KRTAP10-8
KRTAP11-1
KRTAP12-2
KRTAP2-3
KRTAP2-4
KRTAP21-2
KRTAP3-3
KRTAP4-12
KRTAP5-9
KRTAP6-2
KRTAP6-3
LCN2
LDOC1
LMO2
LZTS2
MAGEA11
MAGEA2
MAGEA2B
MAGEA4
MDFI
MIPOL1
MKRN3
MORN3
MRPL38
MSS51
MTUS2
NECAB2
NFKBID
OIP5
OMP
PIK3CA
PLA2G10
PLEKHG4
PNMA1
PPM1D
PRDM14
PTPN11
ROPN1L
SERTAD3
SPRED1
SPRY3
SSX2IP
SYCE1
TACC3
TRAF1
TRAF2
TRIM27
TRIM42
TRIM69
TRIM73
TRIP6
USHBP1
VPS28
ZDHHC17
ZNF19
Entrez ID
3853
84707
HPRD ID
01011
06484
Ensembl ID
ENSG00000205420
ENSG00000133134
Uniprot IDs
A0A0S2Z428
P02538
Q9BXY8
PDB IDs
5KI0
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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