KRT25 and KRT5

Data Source:
BioGRID (two hybrid)

		KRT25	KRT5
Description		keratin 25	keratin 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Molecular_function Structural Molecule Activity Protein Binding Protein Heterodimerization Activity	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Cytoskeleton Organization Aging Hair Follicle Morphogenesis Keratinization Hair Cycle Intermediate Filament Organization Cornification	Cytoskeleton Organization Epidermis Development Keratinization Hemidesmosome Assembly Cornification
Pathways		Keratinization Formation of the cornified envelope	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Dowling-Degos disease Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS		Asthma ( 31959851 30929738) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Basal cell carcinoma ( 31174203 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		22 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT83 KRT85 KRT86 MORN4 PPL	25 interacting genes: ALOX12 ALOX12B APC DSP DST EVPL INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT40 PKP2 TCHP UBE3A
Entrez ID		147183	3852
HPRD ID		17242	01010
Ensembl ID		ENSG00000204897	ENSG00000186081
Uniprot IDs		Q6ZPD6 Q7Z3Z0	P13647
PDB IDs			3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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