CFAP52 and CCT4

Data Source:
HPRD (in vivo)

		CFAP52	CCT4
Description		cilia and flagella associated protein 52	chaperonin containing TCP1 subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Motile Cilium	Zona Pellucida Receptor Complex Nucleoplasm Centrosome Cytosol Chaperonin-containing T-complex Microtubule Melanosome Cell Projection Cell Body Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Cilium Assembly	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS			Erectile dysfunction ( 30583798) Plasma free amino acid levels ( 30659259)
Interacting Genes		3 interacting genes: BRCA2 CCT4 HSPA1A	15 interacting genes: ACTA1 ACTA2 ACTB CCNE1 CCNH CCT2 CFAP52 COP1 LINC01554 MTDH PRPF40A PTEN RPS6KA1 SUMO2 VRK2
Entrez ID		146845	10575
HPRD ID		14072	05506
Ensembl ID		ENSG00000166596	ENSG00000115484
Uniprot IDs		Q8N1V2	P50991
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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