CCT4 and CFAP52

Data Source:
HPRD (in vivo)

		CCT4	CFAP52
Description		chaperonin containing TCP1 subunit 4	cilia and flagella associated protein 52
Image			No pdb structure
GO Annotations	Cellular Component	Zona Pellucida Receptor Complex Nucleoplasm Centrosome Cytosol Chaperonin-containing T-complex Microtubule Melanosome Cell Projection Cell Body Extracellular Exosome	Cytoplasm Motile Cilium
	Molecular Function	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding	Protein Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	Cilium Assembly
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Plasma free amino acid levels ( 30659259)
Interacting Genes		15 interacting genes: ACTA1 ACTA2 ACTB CCNE1 CCNH CCT2 CFAP52 COP1 LINC01554 MTDH PRPF40A PTEN RPS6KA1 SUMO2 VRK2	3 interacting genes: BRCA2 CCT4 HSPA1A
Entrez ID		10575	146845
HPRD ID		05506	14072
Ensembl ID		ENSG00000115484	ENSG00000166596
Uniprot IDs		P50991	Q8N1V2
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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