TTC7B and COG6

Data Source:
BioGRID (two hybrid)

		TTC7B	COG6
Description		tetratricopeptide repeat domain 7B	component of oligomeric golgi complex 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Golgi Membrane Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Phosphatidylinositol Phosphorylation Protein Localization To Plasma Membrane	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Glycosylation
Pathways			COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Anxiety disorder ( 25390645) Cytomegalovirus antibody response ( 21993531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Nevus count or cutaneous melanoma ( 30429480) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma ( 31959851 30929738 32296059) Asthma (adult onset) ( 30929738) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Height ( 31562340) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Psoriasis ( 25903422 18369459) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		5 interacting genes: COG6 FAM126A FAM126B RAB3IL1 RUSC1	66 interacting genes: ARHGEF5 ATXN7 BAIAP2 BCL10 CCDC116 CCDC120 CCDC187 CCDC92 CCHCR1 CNN1 CNNM3 CSRP2 CUL5 DOCK8 DTNB FAM110A FAM90A1 FANCG FNDC11 GAS8 GEM GOLGA2 GRAP2 IGFN1 KANK2 LGALS14 LMO4 MCM7 MFAP1 MRI1 NDUFA5 NEK6 NTAQ1 NUP58 OAS1 PLEKHA2 POM121 PPP1R18 PPP1R32 PSMA1 PSMB1 QARS1 RAB3IL1 RAB6B RSPH14 RTP5 RUNX1T1 SCNM1 SMARCD1 SNAI1 SNAP29 SNRPB SPG21 SYCP2L SYT17 TBC1D22B TMSB4X TSGA10 TSHZ3 TSNAX TTC7B UFSP1 WASHC3 ZBTB16 ZFC3H1 ZNF417
Entrez ID		145567	57511
HPRD ID		18503	08445
Ensembl ID		ENSG00000165914	ENSG00000133103
Uniprot IDs		Q6PIF1 Q86TV6	A0A024RDW5 A0A140VJG7 Q9Y2V7
PDB IDs		5DSE 6BQ1
Enriched GO Terms of Interacting Partners?
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