TTC7B and RAB3IL1

Data Source:
BioGRID (two hybrid)

		TTC7B	RAB3IL1
Description		tetratricopeptide repeat domain 7B	RAB3A interacting protein like 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane	Cytosol Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Phosphatidylinositol Phosphorylation Protein Localization To Plasma Membrane	Exocytosis Protein Transport Regulation Of Catalytic Activity
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Anxiety disorder ( 25390645) Cytomegalovirus antibody response ( 21993531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Nevus count or cutaneous melanoma ( 30429480) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Metabolite levels ( 23823483) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		5 interacting genes: COG6 FAM126A FAM126B RAB3IL1 RUSC1	27 interacting genes: C14orf119 C2orf68 CCDC57 COG6 CTDSP1 CYSRT1 EXOC8 FHL5 HSF2BP IP6K1 KRT34 KRT40 KRTAP6-3 MAP3K1 MTUS2 NBPF19 NOTCH2NLA NUDT18 PSMA3 RAB11A RAB3A RAB3IP RAB8A SATB2 STX1A TIGD7 TTC7B
Entrez ID		145567	5866
HPRD ID		18503	10181
Ensembl ID		ENSG00000165914	ENSG00000167994
Uniprot IDs		Q6PIF1 Q86TV6	Q8TBN0
PDB IDs		5DSE 6BQ1	4LI0
Enriched GO Terms of Interacting Partners?
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