TMEM86A and AQP3

Data Source:
BioGRID (two hybrid)

		TMEM86A	AQP3
Description		transmembrane protein 86A	aquaporin 3 (Gill blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Identical Protein Binding
	Biological Process		Positive Regulation Of Immune System Process Renal Water Homeostasis Water Transport Glycerol Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport Cellular Response To Oxygen-glucose Deprivation
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs			Sennosides
Diseases
GWAS		Ovarian reserve ( 22116950)	Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		47 interacting genes: AQP2 AQP3 BCL2L13 CD79A CISD2 CNR2 COQ9 CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 FXYD3 GJB4 GJB5 GJC1 GORAB GPR37L1 HAVCR2 KASH5 KCNA1 LHFPL5 LMNA MS4A2 MUC1 NCAPH2 PDZK1IP1 PGRMC2 PI16 REEP4 RIC3 RNF185 SCN3B SLC10A6 SLC18A1 SLC30A2 SLC35C2 SLC39A2 SSMEM1 THAP4 TIMMDC1 TMEM31 TMPRSS2 TYROBP	28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN
Entrez ID		144110	360
HPRD ID		08292	08970
Ensembl ID		ENSG00000151117	ENSG00000165272
Uniprot IDs		Q8N2M4	A0A2R8Y2R4 Q92482
PDB IDs
Enriched GO Terms of Interacting Partners?
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