Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TMEM86A and HAVCR2
Data Source:
BioGRID
(two hybrid)
TMEM86A
HAVCR2
Description
transmembrane protein 86A
hepatitis A virus cellular receptor 2
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Immunological Synapse
Early Endosome
Cell Surface
Integral Component Of Membrane
Cell Junction
Molecular Function
Protein Binding
Alkenylglycerophosphocholine Hydrolase Activity
Alkenylglycerophosphoethanolamine Hydrolase Activity
Protein Binding
Metal Ion Binding
Biological Process
Adaptive Immune Response
Macrophage Activation Involved In Immune Response
Natural Killer Cell Tolerance Induction
Regulation Of Tolerance Induction Dependent Upon Immune Response
Negative Regulation Of T-helper 1 Type Immune Response
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Inflammatory Response
Negative Regulation Of Gene Expression
Negative Regulation Of Myeloid Dendritic Cell Activation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-2 Production
Negative Regulation Of Interleukin-3 Production
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Production
Positive Regulation Of Interleukin-4 Production
Positive Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Natural Killer Cell Activation
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 7 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Positive Regulation Of Macrophage Activation
Innate Immune Response
Positive Regulation Of Innate Immune Response
Defense Response To Gram-positive Bacterium
Maternal Process Involved In Female Pregnancy
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Lipopolysaccharide
Negative Regulation Of Granulocyte Colony-stimulating Factor Production
Negative Regulation Of Defense Response To Bacterium
Positive Regulation Of Defense Response To Bacterium
Positive Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Immunological Synapse Formation
Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Pathways
Interleukin-2 family signaling
Drugs
Diseases
GWAS
Ovarian reserve (
22116950
)
Blood protein levels (
30072576
29875488
28240269
)
Hypertriglyceridemia (
23505323
)
Iris heterochromicity (
30895295
)
Interacting Genes
47 interacting genes:
AQP2
AQP3
BCL2L13
CD79A
CISD2
CNR2
COQ9
CPLX4
CREB3L1
EBP
ERGIC3
FAM209A
FFAR2
FKBP7
FNDC9
FXYD3
GJB4
GJB5
GJC1
GORAB
GPR37L1
HAVCR2
KASH5
KCNA1
LHFPL5
LMNA
MS4A2
MUC1
NCAPH2
PDZK1IP1
PGRMC2
PI16
REEP4
RIC3
RNF185
SCN3B
SLC10A6
SLC18A1
SLC30A2
SLC35C2
SLC39A2
SSMEM1
THAP4
TIMMDC1
TMEM31
TMPRSS2
TYROBP
3 interacting genes:
APP
SEC22A
TMEM86A
Entrez ID
144110
84868
HPRD ID
08292
16227
Ensembl ID
ENSG00000151117
ENSG00000135077
Uniprot IDs
Q8N2M4
Q8TDQ0
PDB IDs
5DZL
5F71
6DHB
6TXZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?