CRYBA1 and KLK10

Data Source:
BioGRID (proximity labelling technology)

		CRYBA1	KLK10
Description		crystallin beta A1	kallikrein related peptidase 10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Secretory Granule
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis	Proteolysis Cell Cycle
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)	Blood protein levels ( 30072576)
Interacting Genes		24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3	2 interacting genes: BCAP31 LRIF1
Entrez ID		1411	5655
HPRD ID		00429	04054
Ensembl ID		ENSG00000108255	ENSG00000129451
Uniprot IDs		P05813	O43240
PDB IDs			5LPE 5LPF
Enriched GO Terms of Interacting Partners?
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