Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
RNF32 and EXOSC1
Data Source:
BioGRID
(two hybrid)
RNF32
EXOSC1
Description
ring finger protein 32
exosome component 1
Image
No pdb structure
GO Annotations
Cellular Component
Endosome
Cytosol
Aggresome
Nuclear Body
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Metal Ion Binding
RNA Binding
Exoribonuclease Activity
Protein Binding
Biological Process
RRNA Processing
Regulation Of MRNA Stability
Exonucleolytic Catabolism Of Deadenylated MRNA
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
mRNA decay by 3' to 5' exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Glomerular filtration rate (creatinine) (
26831199
)
Blood protein levels (
30072576
)
Early spontaneous preterm birth (
31194736
)
Spontaneous preterm birth with premature rupture of membranes (
31194736
)
Interacting Genes
42 interacting genes:
A2M
APOE
APP
BLMH
CDC37
CDK5
CEP55
CYP2C8
CYP2C9
ECSIT
ELAVL3
EXOC6
EXOSC1
FARSA
FBXL12
FBXW4
FIBP
GCDH
HOXC4
IFIT3
IFIT5
LONP1
LOXL4
LZTS2
MAST1
MKRN3
MNAT1
NOS3
OGA
PAXIP1
PRAM1
PRDX2
PSEN1
PSEN2
RAB3A
RAB3D
RAD23A
RPP30
STAMBPL1
TRIM23
TRIM74
UBE2K
34 interacting genes:
A2M
APP
ASB9
CDC37
DDIT4L
DMRTB1
ECSIT
EXOC6
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
EXOSC9
FHL3
KCTD1
LNX1
LSM3
MAST1
MPHOSPH6
NOS3
NUP160
PAK5
PTEN
RBPMS
REL
RNF32
SH3GLB2
TCF4
TEX11
UPF2
XRN1
ZNF143
ZNF76
Entrez ID
140545
51013
HPRD ID
11517
16223
Ensembl ID
ENSG00000105982
ENSG00000171311
Uniprot IDs
A0A024RD87
G5E940
Q9H0A6
B1AMU3
Q9Y3B2
PDB IDs
2NN6
6D6Q
6D6R
6H25
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?