NOXA1 and NOXO1

Data Source:
HPRD (two hybrid, in vivo)

		NOXA1	NOXO1
Description		NADPH oxidase activator 1	NADPH oxidase organizer 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Cytoplasm Plasma Membrane NADPH Oxidase Complex
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	Protein Binding Phospholipid Binding Superoxide-generating NADPH Oxidase Activator Activity Enzyme Binding Molecular Adaptor Activity
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Extracellular Matrix Disassembly Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping	RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs			Ecabet
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Red cell distribution width ( 32888494)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	2 interacting genes: NOX1 NOXA1
Entrez ID		10811	124056
HPRD ID		17644	14834
Ensembl ID		ENSG00000188747	ENSG00000196408
Uniprot IDs		Q86UR1	A8K832 Q8NFA2
PDB IDs			2L73
Enriched GO Terms of Interacting Partners?
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