STARD4 and MTIF3

Data Source:
BioGRID (two hybrid)

		STARD4	MTIF3
Description		StAR related lipid transfer domain containing 4	mitochondrial translational initiation factor 3
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Vesicle	Mitochondrion
	Molecular Function	Protein Binding Cholesterol Binding Cholesterol Transfer Activity	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding
	Biological Process	Positive Regulation Of Cholesterol Esterification Cholesterol Transport Involved In Cholesterol Storage Intracellular Cholesterol Transport Cholesterol Import Positive Regulation Of Bile Acid Biosynthetic Process Intermembrane Lipid Transfer	Ribosome Disassembly Mitochondrial Translational Initiation
Pathways		Pregnenolone biosynthesis	Mitochondrial translation initiation
Drugs
Diseases
GWAS		Asthma ( 31959851) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Diisocyanate-induced asthma ( 25918132) Menarche (age at onset) ( 25231870) PR interval ( 32439900)	Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)
Interacting Genes		6 interacting genes: AGTRAP ARL6IP1 CCHCR1 GDAP1 MTIF3 SYP	84 interacting genes: APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202
Entrez ID		134429	219402
HPRD ID		06133	17609
Ensembl ID		ENSG00000164211	ENSG00000122033
Uniprot IDs		B0AZS2 Q96DR4	Q9H2K0
PDB IDs		6L1D 6L1M	6NEQ 6NF8 6RW4 6RW5
Enriched GO Terms of Interacting Partners?
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