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IL31RA and LIFR
Data Source:
HPRD
(in vivo)
IL31RA
LIFR
Description
interleukin 31 receptor A
LIF receptor subunit alpha
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Axon
Presynaptic Membrane
Receptor Complex
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Receptor Complex
Extracellular Exosome
Molecular Function
Transcription Coactivator Activity
Cytokine Receptor Activity
Protein Kinase Binding
Cytokine Binding
Granulocyte Colony-stimulating Factor Binding
Cytokine Receptor Activity
Ciliary Neurotrophic Factor Receptor Activity
Leukemia Inhibitory Factor Receptor Activity
Oncostatin-M Receptor Activity
Ciliary Neurotrophic Factor Receptor Binding
Protein Binding
Growth Factor Binding
Cytokine Binding
Biological Process
MAPK Cascade
Glandular Epithelial Cell Differentiation
Acute Inflammatory Response To Antigenic Stimulus
Defense Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Cell Population Proliferation
Cytokine-mediated Signaling Pathway
Monocyte Differentiation
Macrophage Differentiation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Homeostatic Process
Negative Regulation Of Macrophage Activation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Defense Response To Other Organism
Regulation Of Cytokine-mediated Signaling Pathway
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Cytokine-mediated Signaling Pathway
Response To Cytokine
Oncostatin-M-mediated Signaling Pathway
Leukemia Inhibitory Factor Signaling Pathway
Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways
IL-6-type cytokine receptor ligand interactions
IL-6-type cytokine receptor ligand interactions
RUNX1 regulates transcription of genes involved in interleukin signaling
Drugs
Diseases
Stuve-Wiedemann syndrome
GWAS
Crohn's disease (
23128233
)
Blood protein levels (
30072576
)
Crohn's disease (
26192919
)
Inflammatory bowel disease (
26192919
)
Pursuit maintenance gain (
29064472
)
Ulcerative colitis (
26192919
)
Interacting Genes
2 interacting genes:
IL6ST
LIFR
12 interacting genes:
CNTF
CNTFR
CTF1
IL31RA
IL6ST
LIF
MAPK1
OSM
PLCG1
POU2F1
PTPN11
PTPN6
Entrez ID
133396
3977
HPRD ID
17145
01048
Ensembl ID
ENSG00000164509
ENSG00000113594
Uniprot IDs
B4DNJ2
Q8NI17
A8K1Z4
P42702
PDB IDs
3E0G
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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