COMT and THSD7A

  • Data Source:
  • BioGRID (two hybrid)

COMT

THSD7A

Description catechol-O-methyltransferase thrombospondin type 1 domain containing 7A
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
  • Age at voice drop ( 27182965)
  • Alzheimer's disease (APOE e4 interaction) ( 25778476)
  • Bipolar disorder ( 31043756)
  • Cataracts (operation) ( 31816047)
  • Coronary artery disease ( 29472232)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • End-stage kidney disease ( 31178898)
  • Facial emotion recognition (angry faces) ( 28608620)
  • Glaucoma ( 31959993 30054594)
  • Glaucoma (primary open-angle) ( 29891935)
  • Household income (MTAG) ( 31844048)
  • Idiopathic dilated cardiomyopathy ( 29495422)
  • Intraocular pressure ( 29785010 31959993)
  • Iron status biomarkers (total iron binding capacity) ( 28334935)
  • Lead levels in blood ( 25820613)
  • Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011)
  • Medication use (antiglaucoma preparations and miotics) ( 31015401)
  • Refractive error ( 32231278)
  • Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
  • Resting-state electroencephalogram vigilance ( 29703947)
  • Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009)
  • Tourette syndrome ( 22889924)
Interacting Genes 68 interacting genes: ACE AQP7 AVPR2 BEST2 CCL4L2 CDC27 CDC42 CNR2 CREB3L1 EMD FAM209A FFAR3 GET1 GJB1 GJB3 GJB4 GJB5 GLP1R GPR152 GPR161 GPR42 HIBADH HSD3B7 KCNK5 KRT31 KRT40 KRTAP5-9 LITAF MFSD14B MTNR1A MYADML2 NIPAL4 OTOP3 PGAP2 PLPP6 REEP4 RGS2 RHBDD2 RHBDL1 S1PR3 SELENOK SLC10A6 SLC16A7 SLC2A5 SLC35A4 SLC35F1 SLC39A1 SLC39A2 SLC48A1 SLC7A1 SLC7A8 SMIM1 THSD7A TLCD4 TMEM100 TMEM120B TMEM14B TMEM14C TMEM187 TMEM205 TMEM222 TMEM50A TRHR TRIP13 VAMP3 VAMP5 VKORC1 XRN2 14 interacting genes: AQP6 ARL13B ASAP2 CD33 COMT ELOVL5 GOLM1 HSD17B13 LHFPL1 LYVE1 SCN3B SKIL TMUB2 VMA21
Entrez ID 1312 221981
HPRD ID 00284 19401
Ensembl ID ENSG00000093010 ENSG00000005108
Uniprot IDs A0A140VJG8 P21964 Q9UPZ6
PDB IDs 3A7E 3BWM 3BWY 4PYI 4PYJ 4PYK 4XUC 4XUD 4XUE 5LSA 6I3C 6I3D
Enriched GO Terms of Interacting Partners?
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