CCDC148 and SNX1

Data Source:
BioGRID (two hybrid)

		CCDC148	SNX1
Description		coiled-coil domain containing 148	sorting nexin 1
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process		Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Restless legs syndrome ( 29029846)
Interacting Genes		3 interacting genes: SAT1 SNX1 USHBP1	48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35
Entrez ID		130940	6642
HPRD ID		14046	03171
Ensembl ID		ENSG00000153237	ENSG00000028528
Uniprot IDs		Q8NFR7	Q13596
PDB IDs			2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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