COL9A3 and MAG

Data Source:
HPRD (in vivo)

		COL9A3	MAG
Description		collagen type IX alpha 3 chain	myelin associated glycoprotein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IX Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Paranode Region Of Axon Myelin Sheath Adaxonal Region Myelin Sheath Compact Myelin Schmidt-Lanterman Incisure Membrane Raft Mesaxon
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength	Signaling Receptor Binding Protein Kinase Binding Carbohydrate Binding Sialic Acid Binding Protein Homodimerization Activity Ganglioside GT1b Binding
	Biological Process	Male Gonad Development Female Gonad Development Extracellular Matrix Organization	Cell Adhesion Negative Regulation Of Neuron Projection Development Transmission Of Nerve Impulse Central Nervous System Myelination Negative Regulation Of Axon Extension Axon Regeneration Positive Regulation Of Myelination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Differentiation Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Leukocyte Migration Cellular Response To Mechanical Stimulus Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization	Axonal growth inhibition (RHOA activation) Basigin interactions EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Multiple epiphyseal dysplasia (MED)
GWAS
Interacting Genes		4 interacting genes: COL2A1 EGFR ERBB2 MAG	18 interacting genes: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R
Entrez ID		1299	4099
HPRD ID		00374	01160
Ensembl ID		ENSG00000092758	ENSG00000105695
Uniprot IDs		Q14050	P20916 Q53ES7
PDB IDs		5CTD 5CTI 5CVA 5CVB
Enriched GO Terms of Interacting Partners?
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