MAG and COL9A2

Data Source:
HPRD (in vivo)

		MAG	COL9A2
Description		myelin associated glycoprotein	collagen type IX alpha 2 chain
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Paranode Region Of Axon Myelin Sheath Adaxonal Region Myelin Sheath Compact Myelin Schmidt-Lanterman Incisure Membrane Raft Mesaxon	Extracellular Region Collagen Type IX Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Signaling Receptor Binding Protein Kinase Binding Carbohydrate Binding Sialic Acid Binding Protein Homodimerization Activity Ganglioside GT1b Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Cell Adhesion Negative Regulation Of Neuron Projection Development Transmission Of Nerve Impulse Central Nervous System Myelination Negative Regulation Of Axon Extension Axon Regeneration Positive Regulation Of Myelination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Differentiation Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Leukocyte Migration Cellular Response To Mechanical Stimulus Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Skeletal System Development Extracellular Matrix Organization
Pathways		Axonal growth inhibition (RHOA activation) Basigin interactions EGR2 and SOX10-mediated initiation of Schwann cell myelination	Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs
Diseases			Multiple epiphyseal dysplasia (MED)
GWAS
Interacting Genes		18 interacting genes: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R	10 interacting genes: COL2A1 ERBB2 FEZ1 HAP1 MAG MEOX2 MTNR1A NOA1 UBQLN1 UBQLN2
Entrez ID		4099	1298
HPRD ID		01160	00373
Ensembl ID		ENSG00000105695	ENSG00000049089
Uniprot IDs		P20916 Q53ES7	D3DPU8 Q14055
PDB IDs			5CTD 5CTI 5CVA 5CVB
Enriched GO Terms of Interacting Partners?
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