COL6A1 and DNAJB11

Data Source:
BioGRID (two hybrid)

		COL6A1	DNAJB11
Description		collagen type VI alpha 1 chain	DnaJ heat shock protein family (Hsp40) member B11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type VI Trimer Extracellular Space Lysosomal Membrane Endoplasmic Reticulum Lumen Membrane Protein-containing Complex Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Chaperone Complex
	Molecular Function	Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Platelet-derived Growth Factor Binding	Protein Binding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Osteoblast Differentiation Cell Adhesion Extracellular Matrix Organization Endodermal Cell Differentiation Cellular Response To Amino Acid Stimulus	Protein Folding Positive Regulation Of ATPase Activity IRE1-mediated Unfolded Protein Response Protein Maturation
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization	XBP1(S) activates chaperone genes
Drugs
Diseases		Ossification of the posterior longitudinal ligament of spine (OPLL) Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
GWAS		Blood protein levels ( 30072576 29875488) Bone mineral density (lumbar spine) in inflammatory bowel disease ( 29603369) Corneal hysteresis ( 30894546) Corneal resistance factor ( 31246245 30894546) Diverticular disease ( 30177863) Intraocular pressure ( 29617998 29235454) Myopia ( 27182965) Pulse pressure ( 30224653 30578418) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 28234671) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		10 interacting genes: COL2A1 DCN DNAJB11 FGF7 LAMB1 LGALS3BP MAG MTDH PDGFA PDGFB	24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		1291	51726
HPRD ID		00370	07485
Ensembl ID		ENSG00000142156	ENSG00000090520
Uniprot IDs		A0A384P5H7 P12109	Q9UBS4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?