CYP4F22 and MSMO1

Data Source:
BioGRID (two hybrid)

		CYP4F22	MSMO1
Description		cytochrome P450 family 4 subfamily F member 22	methylsterol monooxygenase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Monooxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Heme Binding	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity
	Biological Process	Icosanoid Metabolic Process Ceramide Biosynthetic Process	Fatty Acid Metabolic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Sterol Biosynthetic Process
Pathways		Fatty acids Miscellaneous substrates Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX) Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)	Cholesterol biosynthesis
Drugs			NADH
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Heel bone mineral density ( 30598549) Neuroticism ( 27067015)
Interacting Genes		4 interacting genes: AQP6 MSMO1 REEP2 TLCD4	18 interacting genes: ATXN1 CHRM5 CYP4F22 DNAJC30 ERG28 GOLT1A GPR35 HMOX1 MMP14 STRIT1 STX3 TMEM11 TMEM140 TMEM242 TMEM65 TMEM86B VKORC1 YIF1A
Entrez ID		126410	6307
HPRD ID		08256	07396
Ensembl ID		ENSG00000171954	ENSG00000052802
Uniprot IDs		Q6NT55	Q15800
PDB IDs
Enriched GO Terms of Interacting Partners?
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