CCR4 and CACNA1H

Data Source:
BioGRID (two hybrid)

		CCR4	CACNA1H
Description		C-C motif chemokine receptor 4	calcium voltage-gated channel subunit alpha1 H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuronal Cell Body	Voltage-gated Sodium Channel Complex Integral Component Of Plasma Membrane Voltage-gated Calcium Channel Complex Integral Component Of Membrane Neuron Projection
	Molecular Function	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Protein Binding Low Voltage-gated Calcium Channel Activity Metal Ion Binding Scaffold Protein Binding
	Biological Process	Neuron Migration Tolerance Induction Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Radiation Response To Bacterium Calcium-mediated Signaling Response To Antibiotic Homeostasis Of Number Of Cells Positive Regulation Of Positive Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway	Muscle Contraction Muscle Organ Development Myoblast Fusion Regulation Of Heart Contraction Neuronal Action Potential Aldosterone Biosynthetic Process Cellular Response To Hormone Stimulus Cortisol Biosynthetic Process Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Cellular Response To Potassium Ion Regulation Of Membrane Potential Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential Inorganic Cation Transmembrane Transport Positive Regulation Of Acrosome Reaction
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	NCAM1 interactions
Drugs		Mogamulizumab FLX475	Ergocalciferol Enflurane Isradipine Spironolactone Cinnarizine Verapamil Zonisamide Felodipine Nitrendipine Nifedipine Bepridil Mibefradil Flunarizine Cannabidiol Trimebutine Benidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Asthma ( 31959851) Celiac disease ( 22057235 20190752) Multiple sclerosis ( 24076602) Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (perceptual aberration scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (revised physical anhedonia scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (revised social anhedonia scale) ( 28525603)	Blood protein levels ( 28240269) Eosinophil counts ( 32888494) Leukocyte telomere length ( 32109421)
Interacting Genes		37 interacting genes: ATP2A2 B3GAT3 BSG CACNA1H CCKBR CCL17 CCL22 CCL3 CCL5 CDK10 CH25H CLASP2 CLPTM1 CNTNAP1 DHCR24 ERGIC3 FAM234A FXR2 GHITM GRK2 GRK3 NAT14 NDRG2 NSUN2 PKM PRDX1 PTOV1 RTN1 RTN4 SLC12A5 SLC3A2 SLCO4A1 STIMATE SYNGR2 TMEM101 TMEM11 TRARG1	3 interacting genes: CCR4 GNG2 KCNMA1
Entrez ID		1233	8912
HPRD ID		05324	07442
Ensembl ID		ENSG00000183813	ENSG00000196557
Uniprot IDs		A0N0Q1 P51679	A0A1W2PQW2 B3KQH9 O95180
PDB IDs
Enriched GO Terms of Interacting Partners?
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