SLAIN1 and PRPF31

Data Source:
BioGRID (two hybrid)

		SLAIN1	PRPF31
Description		SLAIN motif family member 1	pre-mRNA processing factor 31
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton	Nucleus Nucleoplasm U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Identical Protein Binding Ribonucleoprotein Complex Binding SnRNP Binding
	Biological Process		Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome SnoRNA Localization Ribonucleoprotein Complex Localization
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Craniofacial microsomia ( 26853712) Metabolite levels ( 23823483)	Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)
Interacting Genes		44 interacting genes: AKAP9 ARHGEF5 ARMC7 C1orf109 CARD9 COX5B CRACR2A DDX6 DMRTB1 EFHC1 EXOSC8 FAM214B FBXO7 FHL2 FHL3 FRS3 GOLGA1 HNRNPF HOMER3 HOXC8 HSF2BP KCTD9 KIF9 LMO3 MAPRE1 MAPRE3 NDEL1 NTAQ1 NXF1 PATZ1 PAX9 PDLIM7 PFDN5 PPP1R32 PRC1 PRPF31 PSMA3 RBM10 RBM14 RFPL3 TBC1D22B TFAP2D TSSK3 ZNF76	135 interacting genes: ASB15 BHLHB9 BICD2 C1QTNF1 CALCOCO2 CAPNS2 CARD14 CBY2 CCDC106 CCDC136 CCDC33 CCDC57 CCDC70 CCNDBP1 CDC23 CDCA7L CDR2L CEP70 CYSRT1 DVL2 DVL3 EFEMP2 EVI5 FANCA FANCC FASTK FLACC1 FSD2 FXR1 GOLGA2 GOLGA6L9 HAP1 HES7 HNRNPH2 HNRNPK HOOK2 HSF2BP JAKMIP2 KANK2 KCTD6 KHDRBS2 KHDRBS3 KIFC3 KRT15 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP19-5 KRTAP4-11 KRTAP6-3 LBX1 LDOC1 LHX8 LURAP1 LZTS2 MDFI MEIS3 MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NCKIPSD NOTCH2NLA PAK5 PDE4DIP PHC2 PHF5A PICK1 PLEKHG4 PNMA1 PNMA2 PNMA3 PPIH PPP1R16A PPP2R3C PRDM14 PRICKLE1 PRPF3 PSTPIP1 RACK1 RBAK RBM25 RBM4 RBMX RBMY1A1 RBMY1F RBMY1J REL RINT1 RUNDC3A SIAH1 SLAIN1 SNRNP200 SRSF3 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM14 TRIM23 TRIM27 TRIM41 TSGA10 UBXN11 USH1G USP15 VWC2 ZFP64 ZFP69B ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF48 ZNF587 ZNF668 ZNF71 ZNF774 ZNF792 ZNF837 ZRANB1 ZSCAN22
Entrez ID		122060	26121
HPRD ID		13400	05917
Ensembl ID		ENSG00000139737	ENSG00000105618
Uniprot IDs		A0A0A0MSS3 B7Z326 Q7L0J2 Q8ND83	Q8WWY3
PDB IDs			2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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