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PRPF31 and KRT15
Data Source:
BioGRID
(two hybrid)
PRPF31
KRT15
Description
pre-mRNA processing factor 31
keratin 15
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
U2-type Spliceosomal Complex
U4 SnRNP
U4atac SnRNP
Cajal Body
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U2-type Precatalytic Spliceosome
Precatalytic Spliceosome
MLL1 Complex
Spliceosomal Tri-snRNP Complex
Nucleus
Cytosol
Intermediate Filament
Extracellular Exosome
Molecular Function
RNA Binding
Protein Binding
U4 SnRNA Binding
U4atac SnRNA Binding
Identical Protein Binding
Ribonucleoprotein Complex Binding
SnRNP Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Scaffold Protein Binding
Biological Process
Spliceosomal Tri-snRNP Complex Assembly
MRNA Splicing, Via Spliceosome
SnoRNA Localization
Ribonucleoprotein Complex Localization
Cytoskeleton Organization
Epidermis Development
Keratinization
Cornification
Pathways
mRNA Splicing - Major Pathway
Keratinization
Formation of the cornified envelope
Drugs
Diseases
Retinitis pigmentosa (RP)
GWAS
Change in HbA1c levels in response to metformin treatment in type 2 diabetes (
29650774
)
Interacting Genes
135 interacting genes:
ASB15
BHLHB9
BICD2
C1QTNF1
CALCOCO2
CAPNS2
CARD14
CBY2
CCDC106
CCDC136
CCDC33
CCDC57
CCDC70
CCNDBP1
CDC23
CDCA7L
CDR2L
CEP70
CYSRT1
DVL2
DVL3
EFEMP2
EVI5
FANCA
FANCC
FASTK
FLACC1
FSD2
FXR1
GOLGA2
GOLGA6L9
HAP1
HES7
HNRNPH2
HNRNPK
HOOK2
HSF2BP
JAKMIP2
KANK2
KCTD6
KHDRBS2
KHDRBS3
KIFC3
KRT15
KRT31
KRT34
KRT35
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP19-5
KRTAP4-11
KRTAP6-3
LBX1
LDOC1
LHX8
LURAP1
LZTS2
MDFI
MEIS3
MEOX2
MID2
MIPOL1
MKRN3
MTUS2
NCAPH2
NCKIPSD
NOTCH2NLA
PAK5
PDE4DIP
PHC2
PHF5A
PICK1
PLEKHG4
PNMA1
PNMA2
PNMA3
PPIH
PPP1R16A
PPP2R3C
PRDM14
PRICKLE1
PRPF3
PSTPIP1
RACK1
RBAK
RBM25
RBM4
RBMX
RBMY1A1
RBMY1F
RBMY1J
REL
RINT1
RUNDC3A
SIAH1
SLAIN1
SNRNP200
SRSF3
SSX2IP
STX11
TADA2A
TFIP11
TLE5
TMCC2
TP53BP2
TRIM14
TRIM23
TRIM27
TRIM41
TSGA10
UBXN11
USH1G
USP15
VWC2
ZFP64
ZFP69B
ZNF24
ZNF250
ZNF408
ZNF417
ZNF473
ZNF48
ZNF587
ZNF668
ZNF71
ZNF774
ZNF792
ZNF837
ZRANB1
ZSCAN22
145 interacting genes:
ABI2
ABI3
ABLIM1
AMOT
AMOTL2
ANKRD36BP1
APC
ARC
ARFIP2
ATP5PO
BEX2
C1orf216
C2CD6
CALCOCO1
CARD9
CCDC120
CCDC185
CCDC187
CCDC87
CCHCR1
CCNB1IP1
CCNC
CDK18
CEP57
COX5B
CREB5
CYTH4
DEPP1
DES
DEUP1
DGCR6L
DTNB
EFHC1
ENKD1
EPC1
EXOC8
FAM107A
FAM110A
GAS8
GFAP
GLYCTK
HAPLN2
HAUS1
HGS
HMG20B
HOXB6
IKBIP
KANSL1
KDM1A
KIAA0408
KIAA1217
KIFC3
KLC3
KLC4
KRT1
KRT18
KRT19
KRT2
KRT20
KRT4
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT72
KRT73
KRT74
KRT75
KRT77
KRT78
KRT79
KRT8
KRT80
KRT81
KRT82
KRT83
KRT85
KRT86
LDOC1
LMO2
LMO4
LNX1
MAD2L1BP
MBD3
MCM10
MORN3
MOS
NEFL
NIF3L1
NOC4L
NUDT18
NUP54
OIP5
PCM1
PIK3R2
PKN1
PPP1R18
PRPF31
PRPH
PSMA1
PSMB1
PSMC5
RAD51D
RAMAC
RCOR3
RHPN1
RIBC1
RIBC2
RNF6
RPP25
RSPH14
SGF29
SIRPA
SMARCB1
SMARCD1
SMARCE1
SNAPIN
SPG21
SSX2IP
TBC1D21
TCHP
TEKT4
TELO2
TIMM8A
TLE5
TMSB4X
TRIM42
TRIML2
TSG101
TTC23
TUBGCP4
TXLNA
TXLNB
TXNDC11
USHBP1
USP2
WAC
ZC2HC1C
ZFYVE26
ZGPAT
ZNF417
ZNF576
ZNF638
ZNF688
Entrez ID
26121
3866
HPRD ID
05917
01009
Ensembl ID
ENSG00000105618
ENSG00000171346
Uniprot IDs
Q8WWY3
B3KVF5
P19012
PDB IDs
2OZB
3JCR
3SIU
3SIV
5O9Z
6AH0
6AHD
6QW6
6QX9
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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