KRT74 and KRT25

Data Source:
BioGRID (two hybrid)

		KRT74	KRT25
Description		keratin 74	keratin 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Keratin Filament Binding	Molecular_function Structural Molecule Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Keratinization Intermediate Filament Cytoskeleton Organization Cornification	Cytoskeleton Organization Aging Hair Follicle Morphogenesis Keratinization Hair Cycle Intermediate Filament Organization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Woolly hair, including: Autosomal-dominant woolly hair (ADWH); Autosomal-recessive woolly hair (ARWH); Autosomal-recessive woolly hair with or without hypotrichosis
GWAS		Venous thromboembolism ( 32232851)	Asthma ( 31959851 30929738) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		14 interacting genes: KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT31 KRT34 KRT35 KRT37 KRT38 KRT39 LMO4	22 interacting genes: HGS KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT83 KRT85 KRT86 MORN4 PPL
Entrez ID		121391	147183
HPRD ID		10504	17242
Ensembl ID		ENSG00000170484	ENSG00000204897
Uniprot IDs		Q7RTS7	Q6ZPD6 Q7Z3Z0
PDB IDs
Enriched GO Terms of Interacting Partners?
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