CLCNKA and KRT37

Data Source:
BioGRID (two hybrid)

		CLCNKA	KRT37
Description		chloride voltage-gated channel Ka	keratin 37
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Voltage-gated Chloride Channel Activity Identical Protein Binding Metal Ion Binding	Structural Molecule Activity Protein Binding
	Biological Process	Chloride Transport Excretion Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport	Keratinization Cornification
Pathways		Stimuli-sensing channels	Keratinization Formation of the cornified envelope
Drugs		Niflumic acid Talniflumate
Diseases		Bartter syndrome
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left ventricular ejection fraction ( 32382064) Waist circumference adjusted for body mass index ( 28552196)	Squamous cell lung carcinoma ( 28604730)
Interacting Genes		22 interacting genes: C7orf31 CYSRT1 IKZF3 KLHL20 KPRP KRT31 KRT34 KRT37 KRT39 KRTAP21-2 KRTAP4-12 KRTAP6-3 LHX3 MBD3L1 PBX4 SLITRK5 SRPK2 TCF12 TCF4 TEPSIN TRIB3 ZNF511	41 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT3 KRT4 KRT6B KRT6C KRT71 KRT74 KRT75 KRT76 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1
Entrez ID		1187	8688
HPRD ID		03608	05175
Ensembl ID		ENSG00000186510	ENSG00000108417
Uniprot IDs		P51800	O76014
PDB IDs		2PFI
Enriched GO Terms of Interacting Partners?
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