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AP2M1 and LTB4R2
Data Source:
BioGRID
(two hybrid)
AP2M1
LTB4R2
Description
adaptor related protein complex 2 subunit mu 1
leukotriene B4 receptor 2
Image
No pdb structure
GO Annotations
Cellular Component
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
AP-2 Adaptor Complex
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Endolysosome Membrane
Intracellular Membrane-bounded Organelle
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Nucleoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Molecular Function
Signal Sequence Binding
Protein Binding
Lipid Binding
Clathrin Adaptor Activity
Ion Channel Binding
Low-density Lipoprotein Particle Receptor Binding
Leukotriene B4 Receptor Activity
Leukotriene Receptor Activity
G Protein-coupled Peptide Receptor Activity
Biological Process
Intracellular Protein Transport
Endocytosis
Vesicle Budding From Membrane
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Low-density Lipoprotein Particle Receptor Catabolic Process
Low-density Lipoprotein Particle Clearance
Cellular Protein-containing Complex Assembly
Ephrin Receptor Signaling Pathway
Regulation Of Defense Response To Virus By Virus
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Clathrin-dependent Endocytosis
Regulation Of Vesicle Size
Negative Regulation Of Protein Localization To Plasma Membrane
Chemotaxis
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Neuropeptide Signaling Pathway
Leukotriene Signaling Pathway
Pathways
Nef mediated downregulation of CD28 cell surface expression
Nef Mediated CD4 Down-regulation
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Nef Mediated CD8 Down-regulation
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Potential therapeutics for SARS
Leukotriene receptors
G alpha (q) signalling events
Drugs
Amelubant
Leukotriene B4
Diseases
GWAS
Major depressive disorder (
22472876
)
Anorectal malformation (
31136621
)
Height (
28552196
)
Interacting Genes
76 interacting genes:
ADRA1B
AGTR1
AP2B1
AQP4
ARRB2
ATXN1L
BDKRB2
C1orf35
CACNA1A
CD22
CD3D
CDK11B
CORO7
CSNK2B
CTLA4
CXorf51A
CXorf51B
DAB2
DCX
DPPA2
DVL2
EAF1
EHD2
EIF1AD
FAM90A1
FURIN
FXR2
GAK
GRIN2B
H2BC10
H2BC13
H2BC21
H2BC4
H2BC6
H2BC7
H2BC8
HEXIM2
HTR6
IKZF1
KCNJ11
KNOP1
LAMP1
LTB4R2
LY9
MAB21L3
MED4
MEGF10
MFAP1
MPP1
MTURN
NAA11
NCOR2
NDRG1
NKAPD1
PRPF18
PRPF38A
PRR13
PTS
RALBP1
RNF111
RPL22
RPL38
RRP12
RSPH14
RUNDC3A
SFRP4
STON2
SYNJ1
TASOR
TBC1D5
TGOLN2
TMA16
UBC
UTP25
ZBTB8A
ZNF581
46 interacting genes:
AKT1
AP2M1
CANX
CEBPZ
CERS1
CHPT1
CNOT10
CRELD2
CSNK2B
CTSA
DDOST
FOLR1
GJC2
GLOD4
GPR146
GPR37
HLA-A
IL17RD
IMP4
LAMP5
MDH1
MGLL
MYO1E
OBSL1
P4HTM
PER1
PIGM
PKD1
RPN2
SCARB1
SEC13
SGCB
SLC2A1
STMN3
SV2A
SYNGR2
TMED1
TMEM94
TMUB2
TSPAN3
TSPAN4
TSPAN7
TTC9B
VPS25
WFS1
YIF1B
Entrez ID
1173
56413
HPRD ID
03014
16153
Ensembl ID
ENSG00000161203
ENSG00000213906
Uniprot IDs
B4DNB9
E9PFW3
Q96CW1
B4E292
Q9NPC1
PDB IDs
1H6E
6BNT
6URI
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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