AGAP1 and SLC19A3

Data Source:
BioGRID (affinity chromatography technology)

		AGAP1	SLC19A3
Description		ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	solute carrier family 19 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Protein Binding Thiamine Transmembrane Transporter Activity
	Biological Process	Protein Transport Positive Regulation Of GTPase Activity	Thiamine-containing Compound Metabolic Process Transmembrane Transport Thiamine Transmembrane Transport
Pathways			Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Craniofacial microsomia ( 26853712) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Menarche (age at onset) ( 23667675) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31959851 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Obesity-related traits ( 23251661)
Interacting Genes		14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534	15 interacting genes: C3orf38 C4orf3 CREB3 CREB3L4 CYB561 CYP4F2 FXYD6-FXYD2 LAT PLPPR2 TAB2 THBD TMEM14A TMEM14B TMEM242 ZFPL1
Entrez ID		116987	80704
HPRD ID		16359	07311
Ensembl ID		ENSG00000157985	ENSG00000135917
Uniprot IDs		B2RZG9 Q9UPQ3 X5D293	Q9BZV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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