CKMT1B and VDAC1

Data Source:
HPRD (in vitro)

		CKMT1B	VDAC1
Description		creatine kinase, mitochondrial 1B	voltage dependent anion channel 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Extracellular Exosome
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Cholesterol Binding Protein Kinase Binding Phosphatidylcholine Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding Ceramide Binding
	Biological Process	Creatine Metabolic Process Phosphorylation Phosphocreatine Biosynthetic Process	Behavioral Fear Response Pyruvate Metabolic Process Anion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Inorganic Anion Transport Viral Process Macroautophagy Epithelial Cell Differentiation Negative Regulation Of Apoptotic Process Anion Transmembrane Transport Negative Regulation Of Calcium Import Into The Mitochondrion Positive Regulation Of Mitophagy Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Creatine metabolism	Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism Mitochondrial calcium ion transport
Drugs		Creatine Phosphocreatine	Aluminium monostearate Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS			Alopecia areata ( 25608926) Metabolite levels ( 23823483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		13 interacting genes: ASB9 CALM1 CKM CTNNA3 HPCA NUTF2 OCM PPP1R16A PSMC3 RXRG SFRP4 SLC25A5 VDAC1	24 interacting genes: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DUX4 DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PLAT PPIF PRKCE PRKN RAF1 RNF31 SUMO4 TOMM20 TUBA4A
Entrez ID		1159	7416
HPRD ID		00424	05137
Ensembl ID		ENSG00000237289	ENSG00000213585
Uniprot IDs		P12532	A0A1L1UHR1 B3KTS5 P21796
PDB IDs		1QK1	2JK4 2K4T 5JDP 5XDN 5XDO 6G6U 6G73 6TIQ 6TIR
Enriched GO Terms of Interacting Partners?
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